Description

4-Pentenoicacid,2-Amino-3-Cyclopropylidene-(9Ci) is a specialized, non-proteinogenic amino acid derivative featuring a cyclopropylidene and a pentenoic acid moiety, making it a valuable chiral building block for advanced organic synthesis. Its unique structure is critical for constructing complex molecular architectures with high stereochemical control, which is essential for developing novel bioactive compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry for optimal activity.
• Peptidomimetics Research: Serves as a constrained, non-natural amino acid analog for designing and synthesizing peptide mimics with enhanced metabolic stability and binding affinity.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and labeled compounds for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: Acts as a precursor in multi-step synthetic routes for high-value specialty chemicals and advanced materials.

Basic Information

Product Name	4-Pentenoicacid,2-Amino-3-Cyclopropylidene-(9Ci)
CAS No.	205446-90-8
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	2-Amino-3-cyclopropylidene-4-pentenoic acid; (Z)-2-Amino-3-cyclopropylidene-4-pentenoic acid; 2-Amino-3-cyclopropylidenepent-4-enoic acid; 4-Pentenoic acid, 2-amino-3-cyclopropylidene-; (9CI); 205446-90-8; 2-Amino-3-(cyclopropylidene)pent-4-enoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Pentenoicacid,2-Amino-3-Cyclopropylidene-(9Ci) is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral analysis, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.