Description

2-(Trifluoromethyl)-4H-Pyran-4-One is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl group and the pyranone scaffold, enabling the construction of complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethyl moiety into complex molecules via various coupling and cyclization reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new synthetic pathways involving fluorinated heterocycles.

Basic Information

Product Name	2-(Trifluoromethyl)-4H-Pyran-4-One
CAS No.	204516-31-4
Molecular Formula	C6H3F3O2
Molecular Weight	164.08 g/mol
Synonyms	4H-Pyran-4-one, 2-(trifluoromethyl)-; 2-Trifluoromethyl-4H-pyran-4-one; 2-(Trifluoromethyl)-4-pyranone; 4-Oxo-2-(trifluoromethyl)-4H-pyran; 2-(Trifluoromethyl)-4H-pyran-4-one; α-Trifluoromethyl-γ-pyrone
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-4H-Pyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.