Description

Tetrahydro-Furan-3-Ylamine Hcl is a versatile chiral amine building block with a fused furan ring structure. This compound is crucial for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key intermediate for active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereochemistry and functional groups into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereochemical configurations for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	Tetrahydro-Furan-3-Ylamine Hcl
CAS No.	204512-94-7
Molecular Formula	C₄H₉NO•HCl
Molecular Weight	123.58 g/mol (Free base: 87.12 g/mol)
Synonyms	3-Aminotetrahydrofuran hydrochloride; Tetrahydro-3-furanamine hydrochloride; (Tetrahydrofuran-3-yl)amine hydrochloride; 3-Furanamine, tetrahydro-, hydrochloride; THF-3-ylamine HCl; 3-Aminotetrahydrofuran HCl; Tetrahydrofuran-3-amine HCl
EINECS	Contact for details

Quality Control

Our Tetrahydro-Furan-3-Ylamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for assay, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.