Description

(3S,5R)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol is a high-value chiral building block and pharmaceutical intermediate. This compound is significant for its role in the synthesis of complex molecules, particularly in the development of nucleoside analogs and other active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside analogs and antiviral/antitumor drug candidates.
• Biochemical Research: Used as a precursor in the study of carbohydrate metabolism and enzyme inhibitors.
• Asymmetric Synthesis: Serves as a versatile chiral pool starting material for constructing complex natural products and bioactive molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring specific stereochemistry.
• Process Chemistry: Utilized in route scouting and optimization for scalable API manufacturing processes.

Basic Information

Product Name	(3S,5R)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol
CAS No.	204509-32-0
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(3S,5R)-Tetrahydro-5-(hydroxymethyl)-3-furanol; (3S,5R)-5-(Hydroxymethyl)tetrahydro-3-furanol; (3S,5R)-Tetrahydrofuran-3,5-dimethanol (isomer); cis-5-(Hydroxymethyl)tetrahydrofuran-3-ol; (3S,5R)-THF-dimethanol; L-(-)-Ribofuranose derivative; Chiral tetrahydrofuran diol
EINECS	Contact for details

Quality Control

Our (3S,5R)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol is produced under strict quality management systems. We offer material suitable for research and development, with specifications tailored to customer requirements. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.