Description

(1S,5R,6S)-Ethyl 5-(Pentan-3-Yl-Oxy)-7-Oxa-Bicyclo[4.1.0]Hept-3-Ene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex, functionalized bicyclic structure. This compound matters as a critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries working on complex molecule synthesis, particularly in areas requiring stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in medicinal chemistry research.
• Asymmetric Synthesis: Utilized in the construction of stereochemically defined molecular frameworks for new chemical entities (NCEs).
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of target molecules in pilot plants and kilo labs.
• Academic Research: Employed in university and institutional laboratories for methodological studies in organic synthesis and catalysis.
• Fine Chemical Production: Acts as a precursor for specialized agrochemicals, flavors, or fragrances requiring its unique bicyclic ether-oxirane architecture.

Basic Information

Item	Details
Product Name	(1S,5R,6S)-Ethyl 5-(Pentan-3-Yl-Oxy)-7-Oxa-Bicyclo[4.1.0]Hept-3-Ene-3-Carboxylate
CAS No.	204254-96-6
Molecular Formula	C15H24O4
Molecular Weight	268.35 g/mol
Synonyms	Ethyl (1S,5R,6S)-5-[(pentan-3-yl)oxy]-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate; 7-Oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid, 5-[(1-ethylpropyl)oxy]-, ethyl ester, (1S,5R,6S)-; (1S,5R,6S)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester; Chiral oxirane-fused bicyclic ester; Pentan-3-yl oxy substituted 7-oxanorbornene derivative.
EINECS	Contact for details

Quality Control

Our (1S,5R,6S)-Ethyl 5-(Pentan-3-Yl-Oxy)-7-Oxa-Bicyclo[4.1.0]Hept-3-Ene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible quality and supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.