Description

1-Fluorocyclobutanecarboxylic Acid is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclobutane ring substituted with both a carboxylic acid and a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals designed for high-performance applications requiring specific chemical resistance or surface properties.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and novel fluorination methodologies in academic and industrial R&D settings.

Basic Information

Product Name	1-Fluorocyclobutanecarboxylic Acid
CAS No.	202932-09-0
Molecular Formula	C5H7FO2
Molecular Weight	118.11 g/mol
Synonyms	1-Fluorocyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-fluoro-; 1-Fluorocyclobutane-1-carboxylic acid; 1-Fluoro-1-cyclobutanecarboxylic acid; Fluorocyclobutanecarboxylic acid; 202932-09-0; 1-Fluorocyclobutanecarboxylate; 1-Fluorocyclobutylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Fluorocyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizers, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.