Description

2-Bromo-5-Fluorobenzaldoxime is a versatile halogenated aromatic oxime building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic systems.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized chelating ligands used in catalysis and material science.
• Functional Material Synthesis: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for creating molecular probes and tags due to the reactivity of the oxime and halogen functional groups.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form biaryl structures.

Basic Information

Product Name	2-Bromo-5-Fluorobenzaldoxime
CAS No.	202865-62-1
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	5-Fluoro-2-bromobenzaldehyde oxime; (5-Fluoro-2-bromophenyl)methanone oxime; Benzaldehyde, 2-bromo-5-fluoro-, oxime; 2-Bromo-5-fluorobenzaldehyde oxime; α-(Bromo)-5-fluorobenzaldoxime
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluorobenzaldoxime is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.