Description

8-Hydroxy-3,5,7,3',4',5'-Hexamethoxyflavone is a polymethoxylated flavonoid derivative of significant interest in advanced research and development. This compound matters for its role as a key intermediate and reference standard in the synthesis and study of bioactive natural products. Pharmaceutical, nutraceutical, and fine chemical manufacturers require it for developing novel therapeutic agents and high-purity analytical applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel flavonoid-based drugs targeting inflammation and oxidative stress.
• Reference Standard: Used as a high-purity analytical standard in HPLC and LC-MS for quality control of botanical extracts and complex formulations.
• Nutraceutical Research: Investigated for its potential bioactive properties in the development of advanced dietary supplements and functional food ingredients.
• Biochemical Research: Employed in in vitro and in vivo studies to explore mechanisms of action related to its antioxidant and cell-signaling modulation activities.
• Cosmeceutical Development: Evaluated as a potential active ingredient in premium skincare formulations for its purported anti-aging and protective benefits.
• Fine Chemical Synthesis: Acts as a specialized precursor for creating custom flavonoid analogs and derivatives for proprietary chemical libraries.

Basic Information

Item	Details
Product Name	8-Hydroxy-3,5,7,3',4',5'-Hexamethoxyflavone
CAS No.	202846-95-5
Molecular Formula	C21H22O9
Molecular Weight	418.39 g/mol
Synonyms	8-Hydroxy-3,5,6,7,3',4'-Hexamethoxyflavone; 3,5,7,3',4',5'-Hexamethoxy-8-hydroxyflavone; 8-Hydroxyhexamethoxyflavone; Gardenin B; 5,6,7,3',4',5'-Hexamethoxyflavon-8-ol; 5,6,7,3',4',5'-Hexamethoxy-8-hydroxyflavone; 8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-3,5,7,3',4',5'-Hexamethoxyflavone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting research and production standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.