Description

5-(Adamant-1-Yl-Methoxy)-Pentanal is a high-value, functionalized aldehyde derivative of adamantane, a versatile and rigid hydrocarbon cage structure. This compound matters for its role as a key synthetic intermediate, enabling the introduction of the lipophilic and sterically bulky adamantyl group into more complex molecular architectures. It is primarily needed by research chemists and process development teams in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas where the adamantyl moiety can enhance metabolic stability and lipophilicity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore the impact of the adamantane group on drug-like properties such as bioavailability and receptor binding affinity.
• Advanced Material Synthesis: Acts as a monomer or functionalization agent in the development of specialty polymers, dendrimers, and coatings, where the adamantane unit can impart unique thermal stability, rigidity, or solubility characteristics.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis or as a precursor for functionalized materials used in separation sciences and sensor technology.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) and research institutions for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-(Adamant-1-Yl-Methoxy)-Pentanal
CAS No.	202577-32-0
Molecular Formula	C₁₆H₂₆O₂
Molecular Weight	250.38 g/mol
Synonyms	5-((Adamantan-1-yl)methoxy)pentanal; 1-((5-Oxopentyloxy)methyl)adamantane; Pentanal, 5-[(tricyclo[3.3.1.1³,⁷]dec-1-ylmethoxy)]-; Adamant-1-ylmethoxy-pentanal; 5-(Adamantylmethoxy)pentanal; 5-(1-Adamantylmethoxy)pentanal; 202577-32-0; 5-(Adamantan-1-ylmethoxy)pentanal
EINECS	Contact for details

Quality Control

Every batch of 5-(Adamant-1-Yl-Methoxy)-Pentanal is produced and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which typically include identity confirmation by spectroscopic methods (NMR, IR), purity assessment by HPLC or GC, and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistent quality for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed after initial use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.