Description

Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, cis- (9Ci) is a high-purity, functionalized cyclohexane derivative serving as a critical chiral building block in advanced organic synthesis. This compound matters because it provides a stereochemically defined scaffold with both amino and ester functionalities, enabling the construction of complex molecules with precise spatial orientation. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it for developing novel active ingredients, particularly in creating stereocenters for drug candidates and performance chemicals. Its defined cis-configuration ensures consistent and predictable reaction outcomes in multi-step synthetic sequences.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Building block for creating advanced, stereoselective herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, including dyes, flavors, fragrances, and advanced polymer additives.
• Academic and Industrial R&D: Versatile starting material in medicinal chemistry and process chemistry for exploring new synthetic routes and molecular architectures.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, cis- (9Ci)
CAS No.	202120-10-3
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	cis-3-Aminocyclohexanecarboxylic acid methyl ester; Methyl cis-3-aminocyclohexanecarboxylate; (1r,3s)-3-Aminocyclohexanecarboxylic acid methyl ester; Methyl (1r,3s)-3-aminocyclohexanecarboxylate; 3-Amino-cyclohexanecarboxylic acid methyl ester, cis-; cis-Methyl 3-aminocyclohexanecarboxylate; (1R,3S)-Methyl 3-aminocyclohexanecarboxylate; 3-Aminocyclohexanecarboxylic Acid Methyl Ester (cis-)
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Amino-, Methyl Ester, cis- (9Ci) is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.