Description

1,4-Ethano-1H-Cyclopenta[D]Pyridazine,4,4A,5,7A-Tetrahydro-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure, offering significant value in the synthesis of novel active pharmaceutical ingredients (APIs). Its unique bicyclic framework makes it a critical building block for medicinal chemistry research and development, enabling the creation of compounds with targeted biological activity. This intermediate is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and scalable production of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, leveraging its nitrogen-rich heterocyclic core.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, dyes, and functional materials requiring specific fused-ring architectures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic methodology development and bio-active molecule discovery.

Basic Information

Product Name	1,4-Ethano-1H-Cyclopenta[D]Pyridazine,4,4A,5,7A-Tetrahydro-(9Ci)
CAS No.	200276-96-6
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	4,4a,5,7a-Tetrahydro-1H-cyclopenta[d]pyridazine, 1,4-Ethano-; 1,4-Ethano-1H-cyclopenta[d]pyridazine, 4,4a,5,7a-tetrahydro-; 4,4a,5,7a-Tetrahydro-1H-1,4-ethanocyclopenta[d]pyridazine; Bicyclo[3.2.1]oct-6-ene-8-carbonitrile, 1-azabicyclo[3.2.1]oct-6-ene-8-carbonitrile derivative; 1-Azabicyclo[3.2.1]oct-6-ene-8-carbonitrile, 2,3-dihydro-; Contact for additional IUPAC names and research codes.
EINECS	Contact for details

Quality Control

Our 1,4-Ethano-1H-Cyclopenta[D]Pyridazine,4,4A,5,7A-Tetrahydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.