Description

(S)-8-[(6-Ethyl-4-Hydroxy-5-Methyl-2-Oxo-2H-Pyran-3-Yl)Methyl]-2,3-Dihydro-5,7-Dihydroxy-2-Phenyl-4H-1-Benzopyran-4-One is a high-purity, optically active flavonoid derivative with a complex fused pyran-chromone structure. This compound is valued for its role as a key chiral intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation and metabolic diseases.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies and receptor binding assays to investigate flavonoid-related biological pathways.
• Asymmetric Synthesis: Employed as a starting material or catalyst in stereoselective synthesis due to its defined (S)-configuration and multiple functional groups.
• Natural Product Analogue Development: Acts as a core structure for creating synthetic analogues of natural flavonoids with enhanced bioavailability or activity.
• Analytical Standard: Provides a high-purity standard for quality control and method development in HPLC, LC-MS, and chiral analysis within QC laboratories.

Basic Information

Product Name	(S)-8-[(6-Ethyl-4-Hydroxy-5-Methyl-2-Oxo-2H-Pyran-3-Yl)Methyl]-2,3-Dihydro-5,7-Dihydroxy-2-Phenyl-4H-1-Benzopyran-4-One
CAS No.	29881-58-1
Molecular Formula	C24H22O8
Molecular Weight	438.43 g/mol
Synonyms	(S)-8-[(6-Ethyl-4-hydroxy-5-methyl-2-oxo-2H-pyran-3-yl)methyl]-2,3-dihydro-5,7-dihydroxy-2-phenyl-4H-chromen-4-one; (S)-Flavonoid Pyranone Derivative; (S)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-8-[(6-ethyl-4-hydroxy-5-methyl-2-oxo-2H-pyran-3-yl)methyl]-4H-1-benzopyran-4-one; 29881-58-1; (S)-enantiomer of a substituted chromone; L-Form Flavonoid Intermediate
EINECS	Contact for details

Quality Control

Our (S)-8-[(6-Ethyl-4-Hydroxy-5-Methyl-2-Oxo-2H-Pyran-3-Yl)Methyl]-2,3-Dihydro-5,7-Dihydroxy-2-Phenyl-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and optical purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.