Description

Luteolin-7-Glucuronide CAS NO 29741-10-4 is a key bioactive flavonoid glucuronide, a major metabolite of the natural polyphenol luteolin. This compound is valued for its potent antioxidant and anti-inflammatory properties, making it a critical reference standard and active ingredient for research and product development. It is primarily utilized by the pharmaceutical, nutraceutical, and cosmeceutical industries for analytical, preclinical, and formulation purposes.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of luteolin and its metabolites in drug development and pharmacokinetic studies.
• Nutraceutical Ingredient: Incorporated into dietary supplements targeting oxidative stress and inflammation due to its enhanced bioavailability compared to the parent aglycone.
• Cosmetic Actives: Formulated into anti-aging and skin-protective products for its antioxidant capacity and potential to mitigate UV-induced damage.
• Biochemical Research: Serves as a crucial tool for studying flavonoid metabolism, bioavailability, and specific mechanisms of action in cellular and animal models.
• Functional Food & Beverage Fortification: Used to enhance the health-promoting profile of foods and beverages.
• Natural Product Standardization: Essential for standardizing botanical extracts (e.g., from celery, green pepper, chrysanthemum) that contain this metabolite.

Basic Information

Product Name	Luteolin-7-Glucuronide
CAS No.	29741-10-4
Molecular Formula	C21H18O12
Molecular Weight	462.36 g/mol
Synonyms	Luteolin 7-O-β-D-Glucuronide; Luteolin-7-O-glucuronide; 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one; Luteolin 7-glucuronide; 7-Glucuronosylluteolin
EINECS	Contact for details

Quality Control

Our Luteolin-7-Glucuronide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, UV), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.