Description

Apigenin-7-Glucuronide is a major bioactive metabolite of the flavonoid apigenin, formed via glucuronidation in the liver and intestinal tract. This compound is of significant interest for its enhanced bioavailability and potential biological activities compared to its aglycone precursor. It serves as a critical reference standard and active ingredient for researchers and manufacturers in the pharmaceutical, nutraceutical, and cosmeceutical industries, particularly in the development of standardized botanical extracts and advanced therapeutic formulations.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of apigenin metabolites in drug development, pharmacokinetic studies, and bioequivalence testing.
• Nutraceutical Ingredient: Incorporated into dietary supplements and functional foods aimed at providing targeted antioxidant and anti-inflammatory benefits with improved absorption.
• Cosmetic Actives: Formulated into advanced skincare products for its potential skin-soothing, anti-redness, and protective properties against environmental stressors.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the mechanisms of flavonoid metabolism, transport, and receptor interactions.
• Quality Control (QC) for Botanicals: Acts as a marker compound for the standardization and authentication of herbal extracts containing apigenin, such as chamomile and parsley.

Basic Information

Product Name	Apigenin-7-Glucuronide
CAS No.	29741-09-1
Molecular Formula	C21H18O11
Molecular Weight	446.36 g/mol
Synonyms	Apigenin 7-O-β-D-Glucuronide; Apigenin-7-O-glucuronide; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 7-glucuronide; 7-Glucuronylapigenin; Apigenin 7-O-β-D-Glucopyranosiduronic Acid; Apigenin 7-glucuronide; NSC 407303
EINECS	Contact for details

Quality Control

Our Apigenin-7-Glucuronide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (UV, MS, NMR). We provide Certificates of Analysis (COA) with detailed results to ensure compliance with your research or production specifications. For cGMP-grade material or material meeting specific pharmacopeial standards (e.g., as a reference standard), please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (UV)	Conforms to reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.