Description

4-Hydroxy-4'-Iodobiphenyl is a high-purity iodinated biphenyl derivative, serving as a versatile and critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a phenolic hydroxyl group and an iodine substituent on separate phenyl rings, makes it a valuable building block for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for the synthesis of liquid crystals, pharmaceutical active ingredients, and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those requiring a biphenyl core structure.
• Liquid Crystal Materials: Serves as a fundamental building block for the production of advanced liquid crystal compounds used in display technologies (LCDs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Organic Electronic Materials: Acts as a monomer or intermediate in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaics.
• Polymer Modification: Employed to introduce iodine or phenolic functional groups into polymer chains to alter physical properties or enable further chemical reactions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form more complex biaryl systems.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new organic reactions and synthesizing specialized chemical libraries.

Basic Information

Product Name	4-Hydroxy-4'-Iodobiphenyl
CAS No.	29558-78-9
Molecular Formula	C12H9IO
Molecular Weight	296.10 g/mol
Synonyms	4'-Iodo-4-biphenylol; [1,1'-Biphenyl]-4-ol, 4'-iodo-; 4-(4-Iodophenyl)phenol; p-Hydroxy-p'-iodobiphenyl; 4-Hydroxy-4'-iododiphenyl; 4-Iodobiphenyl-4'-ol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-4'-Iodobiphenyl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and relevant physical parameters is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.