Description

tert-Butyl Methylsulfanylformate is a specialized organosulfur compound used as a key synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical manufacturing. This product is essential for chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing thioester or protected carbonyl functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where specific sulfur-containing motifs are required for biological activity.
• Peptide Chemistry: Serves as a reagent in peptide coupling and modification strategies, enabling the introduction of thioester groups.
• Polymer Science: Acts as a monomer or chain-transfer agent in the development of specialty polymers with unique properties.
• Material Science Research: Employed in the synthesis of novel organic materials and ligands for catalysis.
• Cross-Coupling Reactions: Utilized as a substrate in palladium-catalyzed and other transition metal-mediated coupling reactions to form carbon-sulfur bonds.

Basic Information

Product Name	tert-Butyl Methylsulfanylformate
CAS No.	29518-83-0
Molecular Formula	C6H12O2S
Molecular Weight	148.22 g/mol
Synonyms	tert-Butyl thioformate, S-methyl ester; Formic acid, methylthio-, 1,1-dimethylethyl ester; Methylthioformic acid tert-butyl ester; t-Butyl methylthioformate; 1,1-Dimethylethyl methylthioformate; tert-Butyl (methylthio)formate; (tert-Butoxy)thiocarbonyl methanethiolate
EINECS	Contact for details

Quality Control

Our tert-Butyl Methylsulfanylformate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the potential sensitivity of the thioester group, prolonged exposure to elevated temperatures or moisture should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.