Description

(2Alpha,4Aalpha,8Beta)-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalen-8(5H)-One is a high-purity, complex bicyclic ketone with a unique bridged structure, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its ability to impart specific stereochemistry and structural complexity to target molecules, which is essential for developing high-performance materials and active pharmaceutical ingredients (APIs). This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to create novel compounds with precise three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Flavor & Fragrance Ingredient: Serves as a precursor for high-value aroma chemicals with woody, amber, or musky olfactory notes.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of novel polymers with tailored thermal and mechanical properties.
• Asymmetric Catalysis: Utilized as a ligand precursor or a test substrate in the development and screening of new chiral catalysts.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic chemistry, including novel cyclization and rearrangement reactions.

Basic Information

Product Name	(2Alpha,4Aalpha,8Beta)-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalen-8(5H)-One
CAS No.	29461-13-0
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	8-Oxo-1,1,5,5-tetramethyl-2,4-methanohexahydronaphthalene; 1,1,5,5-Tetramethyl-2,4-methano-8-oxohexahydronaphthalene; Tetramethylmethanonaphthalenone; (2α,4aα,8β)-Hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one; 2,4a-Methano-8(5H)-naphthalenone, hexahydro-1,1,5,5-tetramethyl-, (2α,4aα,8β)-; Ambretone (trade name related); Bicyclo[2.2.2]octane derivative
EINECS	Contact for details

Quality Control

Our (2Alpha,4Aalpha,8Beta)-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalen-8(5H)-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to cGMP and ISO 9001 standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.