Description

1,6-Anhydro-2,4-Dideoxy-2,4-Difluoro-β-D-Glucopyranose is a high-value fluorinated carbohydrate derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring a rigid 1,6-anhydro bridge and strategic fluorine substitutions, makes it an essential building block for the development of novel bioactive compounds. This product is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside analogs, antiviral agents, and other fluorinated therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated nucleoside analogs and antiviral drugs, such as potential prodrugs for cancer and viral infection treatments.
• Medicinal Chemistry Research: Used as a scaffold to explore structure-activity relationships (SAR) by introducing fluorine atoms to modulate metabolic stability, bioavailability, and binding affinity.
• Glycochemistry & Glycobiology: Serves as a valuable precursor for constructing complex, fluorinated carbohydrate molecules to study enzyme inhibition and carbohydrate-protein interactions.
• Process Chemistry Development: Employed in route scouting and optimization for the large-scale production of fluorinated active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized to create labeled or tagged molecular probes for investigating biological pathways and mechanisms.

Basic Information

Product Name	1,6-Anhydro-2,4-Dideoxy-2,4-Difluoro-β-D-Glucopyranose
CAS No.	29332-85-2
Molecular Formula	C6H6F2O4
Molecular Weight	180.11 g/mol
Synonyms	2,4-Dideoxy-2,4-difluoro-1,6-anhydro-β-D-glucopyranose; 1,6-Anhydro-2,4-dideoxy-2,4-difluoro-β-D-glucose; 2,4-Difluoro-1,6-anhydro-2,4-dideoxy-β-D-glucopyranose; β-D-1,6-Anhydro-2,4-dideoxy-2,4-difluoroglucopyranose; 29332-85-2; 1,6-Anhydro-2,4-difluoro-2,4-dideoxy-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 1,6-Anhydro-2,4-Dideoxy-2,4-Difluoro-β-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.