Description

α-Bromo-2-Methylphenylacetic Acid is a versatile brominated aromatic acid derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its value lies in its reactive bromine atom and carboxylic acid functionality, enabling precise chemical modifications for creating complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other chiral therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Chiral Auxiliary & Ligand Preparation: Serves as a starting material for synthesizing chiral auxiliaries and ligands used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex organic molecules for material science and electronic chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling reactions and stereoselective transformations.

Basic Information

Product Name	α-Bromo-2-Methylphenylacetic Acid
CAS No.	29302-73-6
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	2-(2-Methylphenyl)-2-bromoacetic acid; (2-Bromo-2-(2-methylphenyl))acetic acid; o-Methyl-α-bromophenylacetic acid; 2-Methylbenzeneacetic acid, α-bromo-; Bromo(o-tolyl)acetic acid; α-Bromo-2-methylbenzeneacetic acid; BROMO(O-TOLYL)ACETIC ACID; (2-Methylphenyl)(bromo)acetic acid
EINECS	Contact for details

Quality Control

Our α-Bromo-2-Methylphenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.