Description

2-Chloro-4-Methoxynitrobenzene is a versatile halogenated aromatic nitro compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring distinct chloro, methoxy, and nitro substituents, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where its substituted benzene ring is incorporated into the final product.
• Dye and Pigment Manufacturing: Serves as a starting material for producing azo dyes and other colored compounds, leveraging its nitro group for subsequent reduction and diazotization reactions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the 2-chloro-4-methoxyphenyl moiety into more complex structures.
• Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical entities in material science and medicinal chemistry.
• Liquid Crystal and Electronic Material Precursor: Can be used in the synthesis of advanced organic materials requiring specific aromatic units with electron-withdrawing and donating groups.

Basic Information

Product Name	2-Chloro-4-Methoxynitrobenzene
CAS No.	28987-59-9
Molecular Formula	C7H6ClNO3
Molecular Weight	187.58 g/mol
Synonyms	1-Chloro-2-Methoxy-5-Nitrobenzene; 2-Chloro-4-Methoxy-1-Nitrobenzene; 4-Methoxy-2-Chloronitrobenzene; 5-Nitro-2-Chloroanisole; 2-Chloro-4-Methoxynitrobenzene; 2-Chloro-4-Methoxy Nitrobenzene; 2-Chloro-4-Methoxynitrobenzene; 2-Chloro-4-Methoxy Nitro Benzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxynitrobenzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, assay, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate and in other critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.