Description

Benzyl 2-O,3-o-Isopropylidene-α-D-Mannofuranoside Bis(Methanesulfonate) is a high-purity, protected carbohydrate derivative and a key synthetic intermediate in organic and medicinal chemistry. Its primary value lies in its role as a versatile building block for the controlled synthesis of complex oligosaccharides, glycoconjugates, and nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly in the development of antiviral agents, carbohydrate-based vaccines, and other bioactive molecules where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Serves as a protected mannose donor for the stepwise construction of complex oligosaccharides and glycoconjugates.
• Carbohydrate Chemistry: Used in the development of novel glycosylation methodologies and the study of carbohydrate-protein interactions.
• Bioconjugate Development: Enables the creation of labeled sugars or sugar-linked probes for diagnostic and biochemical applications.
• Process Chemistry: Employed in scale-up routes for the production of active pharmaceutical ingredients (APIs) requiring specific sugar motifs.

Basic Information

Product Name	Benzyl 2-O,3-o-Isopropylidene-α-D-Mannofuranoside Bis(Methanesulfonate)
CAS No.	28978-37-2
Molecular Formula	C₁₈H₂₆O₁₀S₂
Molecular Weight	466.52 g/mol
Synonyms	Benzyl 2,3-O-Isopropylidene-α-D-mannofuranoside Bis(methanesulfonate); 1-O-Benzyl-2,3-O-isopropylidene-α-D-mannofuranoside 5,6-Bis(methanesulfonate); α-D-Mannofuranoside, benzyl 2,3-O-(1-methylethylidene)-, 5,6-bis(methanesulfonate); Benzyl 2,3-O-Isopropylidene-α-D-mannofuranoside 5,6-Dimesylate; 5,6-Bis-O-methanesulfonyl-1-O-benzyl-2,3-O-isopropylidene-α-D-mannofuranose
EINECS	Contact for details

Quality Control

Our Benzyl 2-O,3-o-Isopropylidene-α-D-Mannofuranoside Bis(Methanesulfonate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a desiccated environment to prevent degradation. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.