Description

Methyl Toluenesulfonate CAS NO 28804-47-9 is a versatile organic sulfonate ester, specifically the methyl ester of p-toluenesulfonic acid, valued for its role as an effective alkylating agent and protecting group reagent in complex synthetic pathways. Its importance lies in its ability to introduce methyl groups or act as a leaving group in nucleophilic substitution reactions, enabling the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for R&D chemists and production specialists in the pharmaceutical, fine chemical, and polymer industries who require high-purity intermediates for scalable and reliable synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in methylation and sulfonylation reactions.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where its sulfonate group is integral to the final molecule's activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, ion-exchange resins, and functional materials.
• Fine Chemical Manufacturing: Employed as a reagent for protecting hydroxyl groups during multi-step organic synthesis.
• Dye & Pigment Production: Acts as an intermediate in the synthesis of sulfonated dyes and colorants.
• Laboratory Research: A standard reagent in academic and industrial R&D for method development and exploratory chemistry.

Basic Information

Product Name	Methyl Toluenesulfonate
CAS No.	28804-47-9
Molecular Formula	C8H10O3S
Molecular Weight	186.23 g/mol
Synonyms	Methyl p-Toluenesulfonate; Methyl Tosylate; p-Tolyl methyl sulfonate; Methyl 4-methylbenzenesulfonate; Tosic Acid Methyl Ester; 4-Methylbenzenesulfonic Acid Methyl Ester; Methyl Paratoluenesulfonate; MTS
EINECS	249-230-8

Quality Control

Our Methyl Toluenesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chromatography and spectroscopy, to confirm identity and meet specified impurity profiles. Certificates of Analysis (COA) documenting purity, assay, and related substances are available for every batch upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect product quality. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.20 - 1.25

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.