Description

[S,(-)]-2,3,4,4A,5,6-Hexahydro-1,4A-Dimethyl-7-(1-Methylethyl)Naphthalene is a high-purity, chiral decalin derivative with a complex stereochemistry that makes it a valuable synthetic intermediate. This compound matters for its role in the synthesis of complex organic molecules, particularly in the pharmaceutical and fragrance industries where specific stereochemistry is critical for biological activity and odor profile. It is needed by research chemists and process development teams working on advanced synthetic routes, as well as by manufacturers of fine chemicals and specialty aroma chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly those with a decalin or terpenoid core structure.
• Fragrance and Flavor Synthesis: Used in the production of high-value aroma chemicals, contributing woody, amber, or musky notes due to its complex terpenoid-like structure.
• Organic Synthesis Research: Acts as a versatile starting material or intermediate in academic and industrial research for developing new synthetic methodologies.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, stereospecific pesticides or plant growth regulators.
• Catalyst and Ligand Development: The rigid, chiral framework can be utilized to develop novel asymmetric catalysts or ligands for enantioselective reactions.

Basic Information

Product Name	[S,(-)]-2,3,4,4A,5,6-Hexahydro-1,4A-Dimethyl-7-(1-Methylethyl)Naphthalene
CAS No.	28624-23-9
Molecular Formula	C15H24
Molecular Weight	204.35 g/mol
Synonyms	(-)-Ambrox; (S)-(-)-Ambroxide; (S)-(-)-Ambroxan; (S)-(-)-Ambrox DL; (S)-(-)-2,3,4,4a,5,6,7,8-Octahydro-1,1,4a,7-tetramethylnaphthalene; (S)-(-)-1,1,4a,7-Tetramethyl-2,3,4,4a,5,6,7,8-octahydronaphthalene; (S)-(-)-Amberketal; (S)-(-)-Ambrox Super
EINECS	Contact for details

Quality Control

Our [S,(-)]-2,3,4,4A,5,6-Hexahydro-1,4A-Dimethyl-7-(1-Methylethyl)Naphthalene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (GC, HPLC) and optical rotation values are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are properly sealed and stored upright to minimize loss. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (S-isomer)
Optical Rotation [α]20/D	Contact for details
Specific Gravity	Contact for details
Refractive Index	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.