Description

3-Oxetanecarboxylic Acid, 3-Methyl is a versatile and highly functionalized oxetane derivative, serving as a critical chiral building block in advanced organic synthesis. Its strained four-membered oxetane ring and carboxylic acid functionality make it a valuable precursor for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific stereochemical configurations for optimal activity.
• Ligand and Catalyst Development: Employed as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with unique thermal or mechanical properties.
• Peptidomimetics & Bioisosteres: The oxetane ring is used as a bioisostere for carbonyl or gem-dimethyl groups in medicinal chemistry to improve metabolic stability and pharmacokinetic properties.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in exploring new synthetic methodologies and ring-opening reactions.

Basic Information

Product Name	3-Oxetanecarboxylic Acid, 3-Methyl
CAS No.	28562-68-7
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	3-Methyl-3-oxetanecarboxylic Acid; 3-Methyloxetane-3-carboxylic Acid; (3-Methyloxetan-3-yl)methanoic Acid; 3-Oxetanecarboxylic acid, 3-methyl-; 3-Methyloxetane-3-carboxylate; 3-Methyl-3-carboxyoxetane; 3-Methyloxetane-3-carboxylic acid; 3-Methyl-3-oxetanylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-3-oxetanecarboxylic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.