Description

Pyridazine-3-Thiol is a versatile heterocyclic building block featuring a thiol group on the pyridazine ring, making it a valuable intermediate for synthesizing complex molecules. Its primary commercial value lies in its role as a key precursor in pharmaceutical research and development, particularly for creating novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its heterocyclic structure.
• Ligand for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal catalysis for fine chemical synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and electronic materials.
• Bioconjugation Chemistry: The thiol group allows for use in bioconjugation techniques, linking molecules to proteins or other biomolecules.
• Chemical Biology Probes: Useful for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	Pyridazine-3-Thiol
CAS No.	28544-77-6
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	3-Pyridazinethiol; 3-Mercaptopyridazine; 1,2-Diazine-3-thiol; Pyridazine-3-thione (tautomer); 3-Thiolpyridazine; 3H-Pyridazine-3-thione; 1,2-Diazin-3-thiol
EINECS	Contact for details

Quality Control

Our Pyridazine-3-Thiol is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.