Description

Poly(Nipam-Co-Acrylamide) is a synthetic, temperature-responsive copolymer of N-isopropylacrylamide (NIPAM) and acrylamide. This material is engineered to exhibit a sharp lower critical solution temperature (LCST) phase transition, making it a critical component in advanced material science and biotechnology. It is essential for researchers and manufacturers in the pharmaceutical, biomedical, and smart material sectors who require precise control over solubility and gelation properties for innovative applications.

Application

• Drug Delivery Systems: As a key component in thermosensitive hydrogels for controlled and targeted release of active pharmaceutical ingredients.
• Biomedical Research: Used in cell culture substrates, tissue engineering scaffolds, and bioseparation technologies that leverage its reversible phase transition.
• Smart Materials & Sensors: Incorporated into actuators, valves, and optical sensors where a response to temperature change is required.
• Cosmetics & Personal Care: Utilized in formulating advanced skincare products for its film-forming and viscosity-modifying properties.
• Chromatography & Purification: Serves as a stationary phase or modifier in affinity chromatography for protein separation.
• Enhanced Oil Recovery (EOR): Acts as a viscosity modifier in polymer flooding applications to improve oil displacement efficiency.

Basic Information

Product Name	Poly(Nipam-Co-Acrylamide)
CAS No.	28500-83-6
Molecular Formula	(C6H11NO)x(C3H5NO)y
Molecular Weight	Variable (Polymer)
Synonyms	Poly(N-isopropylacrylamide-co-acrylamide); PNIPAM-co-PAAm; Thermoresponsive Poly(NIPAM-AAm); NIPAM-Acrylamide Copolymer; p(NIPAM-co-AAm); Poly(N-isopropylacrylamide/acrylamide); LCST Copolymer; Smart Polymer
EINECS	Contact for details

Quality Control

Our Poly(Nipam-Co-Acrylamide) is produced under stringent quality management protocols. Each batch is characterized for critical parameters including monomer ratio, molecular weight distribution, and phase transition temperature to ensure batch-to-batch consistency for your research and production needs. Certificates of Analysis (COA) detailing specifications such as composition, residual monomers, and LCST are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Composition (NIPAM:AAm Ratio)	As per customer requirement (e.g., 90:10, 80:20)
Molecular Weight (GPC)	Customizable (e.g., 10k - 500k Da)
Lower Critical Solution Temperature (LCST)	Specified range (e.g., 32-40°C)
Residual Monomers (HPLC)	< 0.5%
Moisture Content (KF Titration)	< 5.0%
Solubility	Soluble in water and select organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.