Description

[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulene-6-Carboxaldehyde is a high-purity, complex sesquiterpene aldehyde building block prized for its unique and rigid molecular architecture. This compound matters as a critical chiral intermediate for synthesizing advanced fragrance molecules, pharmaceuticals, and fine chemicals where stereochemical control is paramount. It is primarily needed by R&D chemists and process development teams in the flavor & fragrance, pharmaceutical, and specialty chemical industries seeking to leverage its distinctive bicyclic framework.

Application

• Fragrance & Flavor Intermediate: A key chiral precursor for the synthesis of sophisticated amber, woody, and musk odorants.
• Pharmaceutical Research: Serves as a versatile scaffold in medicinal chemistry for developing novel therapeutic agents.
• Organic Synthesis: Used as a building block for complex natural product synthesis and asymmetric catalysis studies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable compound for research into terpene chemistry and novel synthetic methodologies.

Basic Information

Product Name	[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulene-6-Carboxaldehyde
CAS No.	28387-62-4
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	6-Formyl-3,8,8-trimethyl-2,3,4,7,8,8a-hexahydro-1H-3a,7-methanoazulene; (3R,3aS,7R,8aR)-3,8,8-Trimethyl-2,3,4,7,8,8a-hexahydro-1H-3a,7-methanoazulene-6-carbaldehyde; Ambrialdehyde; 3,8,8-Trimethyl-2,3,4,7,8,8a-hexahydro-1H-3a,7-methanoazulene-6-carboxaldehyde; Sesquiterpene aldehyde (Ambrialdehyde type)
EINECS	Contact for details

Quality Control

Our [3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulene-6-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This product is easily oxidized and light-sensitive; minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.