Description

2-Hydroxypropyl 4-Oxo-4-[(Tributylstannyl)Oxy]Isocrotonate is a specialized organotin compound that serves as a valuable intermediate in advanced organic synthesis. Its structure, featuring both a stannyl ester and a reactive keto-acrylate moiety, makes it a versatile building block for constructing complex molecules. This product is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly where organotin-mediated coupling or transfer reactions are required.
• Agrochemical Synthesis: Serves as a key precursor in the development of new pesticides, herbicides, and fungicides.
• Polymer Chemistry: Acts as a functional monomer or catalyst component in the production of specialty polymers and materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for Stille-type cross-coupling reactions and other organometallic transformations.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value fine chemicals and flavors/fragrances.
• Material Science Research: Investigated for use in creating novel organometallic frameworks and advanced catalytic systems.

Basic Information

Product Name	2-Hydroxypropyl 4-Oxo-4-[(Tributylstannyl)Oxy]Isocrotonate
CAS No.	28375-10-2
Molecular Formula	C18H34O5Sn
Molecular Weight	449.16 g/mol
Synonyms	4-[(Tributylstannyl)oxy]-4-oxo-2-butenoic acid 2-hydroxypropyl ester; Tributyltin 4-Oxo-4-(2-hydroxypropoxy)-2-butenoate; 2-Hydroxypropyl (E)-4-oxo-4-(tributylstannyloxy)but-2-enoate; Isocrotonic acid, 4-oxo-4-(tributylstannyloxy)-, 2-hydroxypropyl ester; Tributylstannyl 4-Oxoisocrotonate 2-Hydroxypropyl Ester; Organotin Acrylate Ester Intermediate; TBTO Acrylate Derivative
EINECS	Contact for details

Quality Control

Our 2-Hydroxypropyl 4-Oxo-4-[(Tributylstannyl)Oxy]Isocrotonate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial use. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to the organotin content, handle and store with appropriate safety precautions in accordance with local regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Tributyltin Hydroxide (Impurity)	≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.