Description

Aloin B CAS NO 28371-16-6 is a purified, bioactive anthrone C-glycoside primarily isolated from the Aloe vera plant. This compound serves as a critical reference standard and active pharmaceutical ingredient (API) for research and development in the pharmaceutical and nutraceutical sectors. It is essential for manufacturers and research institutions focused on botanical extracts, gastrointestinal therapeutics, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of aloe-derived products in pharmacopoeial methods (e.g., USP, EP).
• Active Pharmaceutical Ingredient (API): Serves as a key component in the formulation of botanical drugs targeting digestive health and laxative effects.
• Nutraceutical & Dietary Supplement Manufacturing: Incorporated into standardized aloe vera extracts to ensure consistent potency and bioactivity.
• Biomedical & Pharmacological Research: Utilized in in-vitro and in-vivo studies to investigate anti-inflammatory, antimicrobial, and potential anticancer properties.
• Cosmeceutical Development: Applied in high-end skincare formulations for its purported bioactive properties, requiring high-purity actives.
• Analytical Chemistry: Functions as a critical calibration standard for HPLC, LC-MS, and TLC methods in quality assurance laboratories.

Basic Information

Product Name	Aloin B
CAS No.	28371-16-6
Molecular Formula	C21H22O9
Molecular Weight	418.39 g/mol
Synonyms	Barbaloin; Aloin A; 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone; (10R)-Aloin B; 1,8-Dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracen-9(10H)-one; Aloe-emodin anthrone C-glucoside; Aloin (mixture of A & B isomers)
EINECS	Contact for details

Quality Control

Our Aloin B is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards for pharmaceutical reference materials. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP guidelines and relevant pharmacopoeial monographs (USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0% (on dried basis)
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Related Substances (HPLC)	Total impurities ≤5.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.