Description

1-Amino-1-Cyclooctanecarboxylic Acid is a specialized, non-proteinogenic amino acid featuring a cyclooctane ring, which imparts unique conformational and steric properties. This compound is a valuable chiral building block in advanced organic synthesis, particularly for the development of novel pharmacophores and constrained peptides. It is primarily utilized by pharmaceutical research organizations and fine chemical manufacturers focused on creating new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of new drug candidates, especially for creating conformationally restricted peptide mimetics.
• Peptidomimetics & Bioactive Peptides: Used to introduce structural constraints into peptide chains, enhancing metabolic stability and target selectivity.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective reactions to construct complex molecules with defined stereochemistry.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tools to study biological processes and protein interactions.
• Agrochemical Development: Potential use in the synthesis of novel, high-performance active ingredients for crop protection.
• Material Science: Can be incorporated into specialty polymers or coatings to modify physical and chemical properties.

Basic Information

Product Name	1-Amino-1-Cyclooctanecarboxylic Acid
CAS No.	28248-38-6
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	1-Aminocyclooctane-1-carboxylic Acid; 1-Amino-1-cyclooctanecarboxylic acid; Cyclooctane-1-carboxylic acid, 1-amino-; 1-Amino-cyclooctanecarboxylic acid; ACCA; 1-Cyclooctylglycine; (1-Aminocyclooctyl)carboxylic acid; 1-Amino-cyclooctyl-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Amino-1-Cyclooctanecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.