Description

1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-β-D-Fructofuranose [Phosphoric Acid Bis(Trimethylsilyl)] Ester is a highly specialized, fully protected derivative of fructose, designed for advanced synthetic applications where precise control over hydroxyl group reactivity is paramount. This compound serves as a critical synthetic intermediate, enabling the selective manipulation of carbohydrate frameworks in complex organic synthesis. It is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and advanced materials science who require high-purity, protected building blocks for glycosylation and nucleoside chemistry.

Application

• Pharmaceutical Intermediate: Key protected synthon for the synthesis of novel nucleoside analogs, antiviral agents, and complex carbohydrate-based therapeutics.
• Glycosylation Reagent: Used in the stereoselective construction of oligosaccharides and glycoconjugates for biological studies and drug discovery.
• Agrochemical Synthesis: Serves as a building block for developing advanced, sugar-derived pesticides and plant growth regulators.
• Chemical Biology Probe Development: Enables the creation of labeled or modified sugars for studying metabolic pathways and enzyme mechanisms.
• Advanced Material Precursor: Utilized in the research and development of specialty polymers and surfactants with carbohydrate backbones.
• Process Chemistry: Provides a stable, silyl-protected intermediate for scalable manufacturing processes requiring selective deprotection strategies.

Basic Information

Item	Details
Product Name	1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-β-D-Fructofuranose [Phosphoric Acid Bis(Trimethylsilyl)] Ester
CAS No.	28176-76-3
Molecular Formula	C24H61O9PSi6
Molecular Weight	677.28 g/mol
Synonyms	Fructofuranose, 1,2,3,4-tetrakis-O-(trimethylsilyl)-, cyclic 1,2-(hydrogen phosphate) P,P-bis(trimethylsilyl) ester, β-D-; 1,2,3,4-Tetrakis-O-(trimethylsilyl)-β-D-fructofuranose cyclic 1,2-(hydrogen phosphate) P,P-bis(trimethylsilyl) ester; Fully Silylated Fructose Phosphate Ester; TMS-Fructofuranose Phosphate; Per-O-trimethylsilyl β-D-fructofuranose 1,2-cyclic phosphate bis(trimethylsilyl) ester; Protected Fructose Phosphate Intermediate
EINECS	Contact for details

Quality Control

Our 1-O,2-O,3-O,4-o-Tetrakis(Trimethylsilyl)-β-D-Fructofuranose [Phosphoric Acid Bis(Trimethylsilyl)] Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.