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Rel-(1R*,2S*)-2-Hydroxy-1-Cyclohexanecarboxylic Acid CAS NO 28131-61-5


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CAS No.:28131-61-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rel-(1R*,2S*)-2-Hydroxy-1-Cyclohexanecarboxylic Acid is a chiral, cyclic hydroxycarboxylic acid derivative that serves as a valuable synthetic intermediate and building block in advanced organic synthesis. Its defined stereochemistry and bifunctional nature make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

  • Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and enzyme inhibitors.
  • Asymmetric Synthesis: Used as a precursor for chiral auxiliaries, ligands, and catalysts in stereoselective chemical reactions.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
  • Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
  • Polymer Chemistry: Potential monomer or co-monomer for creating functionalized polymers with tailored properties.

Basic Information

Product Name Rel-(1R*,2S*)-2-Hydroxy-1-Cyclohexanecarboxylic Acid
CAS No. 28131-61-5
Molecular Formula C7H12O3
Molecular Weight 144.17 g/mol
Synonyms rel-(1R,2S)-2-Hydroxycyclohexane-1-carboxylic Acid; (±)-trans-2-Hydroxycyclohexanecarboxylic Acid; trans-2-Hydroxycyclohexanecarboxylic Acid; 2-Hydroxycyclohexanecarboxylic Acid (trans-); Cyclohexanecarboxylic acid, 2-hydroxy-, (1R,2S)-rel-; 1-Cyclohexanecarboxylic acid, 2-hydroxy-, (1R*,2S*)-rel-; (±)-trans-2-Hydroxy-1-cyclohexanecarboxylic Acid
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Quality Control

Our Rel-(1R*,2S*)-2-Hydroxy-1-Cyclohexanecarboxylic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data for assay, chiral purity, and specific impurity profiles. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect product quality and stability. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% de (trans-isomer)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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