Description

Tigladoxime CAS NO 28052-08-6 is a high-purity oxime compound primarily used as a key intermediate in the synthesis of advanced pharmaceutical agents and fine chemicals. Its significance lies in its role as a versatile building block for constructing complex molecules, enabling the development of new therapeutic candidates and specialty materials. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers seeking reliable, high-quality intermediates for their synthesis workflows.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its oxime functionality is key to biological activity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and functional materials.
• Research & Development: Employed in academic and industrial R&D for method development and the exploration of new chemical entities.
• Cross-Coupling Reactions: Acts as a ligand or intermediate in metal-catalyzed coupling reactions for constructing complex organic frameworks.
• Polymer Modification: Utilized to introduce specific functional groups into polymer chains to alter material properties.

Basic Information

Product Name	Tigladoxime
CAS No.	28052-08-6
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	2-Butanone oxime, 3-methyl-; 3-Methylbutan-2-one oxime; Tiglic aldehyde oxime; Tigladoxim; Tiglic acid oxime; 3-Methyl-2-butanone oxime; Tiglic aldehyde, oxime; (E)-3-Methylbutan-2-one oxime
EINECS	248-828-7

Quality Control

Our Tigladoxime is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.