Description

1,1-Dimethyl-3-[3-(1,1,2,2-Tetrafluoroethoxy)Phenyl]Urea is a specialized fluorinated urea derivative, a key intermediate in advanced chemical synthesis. Its value lies in the unique combination of the urea pharmacophore with a tetrafluoroethoxy substituent, which can impart enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily required by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for improved bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or plant growth regulators, where the fluorinated side chain can influence biological activity and environmental persistence.
• Chemical Biology Probe: Acts as a scaffold or modifier in the design of molecular probes for studying enzyme inhibition or protein-ligand interactions in biochemical assays.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or coatings where fluorine incorporation is desired for properties like chemical resistance or low surface energy.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers offering bespoke synthesis services for client-specific fluorinated target molecules.

Basic Information

Product Name	1,1-Dimethyl-3-[3-(1,1,2,2-Tetrafluoroethoxy)Phenyl]Urea
CAS No.	27954-37-6
Molecular Formula	C11H12F4N2O2
Molecular Weight	280.22 g/mol
Synonyms	N,N-Dimethyl-N'-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]urea; 3-(1,1,2,2-Tetrafluoroethoxy)phenyl dimethylurea; Urea, 1,1-dimethyl-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-; 1,1-Dimethyl-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)urea; [3-(1,1,2,2-Tetrafluoroethoxy)phenyl]dimethylurea
EINECS	Contact for details

Quality Control

Our 1,1-Dimethyl-3-[3-(1,1,2,2-Tetrafluoroethoxy)Phenyl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.