Description

[2,5-Bis(Trimethylsilyloxy)Phenyl]Acetic Acid Methyl Ester is a high-purity organosilicon derivative, valued as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis. Its unique structure, featuring two silyl-protected phenolic hydroxyl groups, makes it a critical building block for constructing complex molecules with precise functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected phenol functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its silicon-based protecting groups offer selective reactivity.
• Advanced Material Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, silicones, and organic electronic materials.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the [2,5-bis(trimethylsilyloxy)phenyl]acetyl moiety into target molecules in medicinal and combinatorial chemistry.
• Protecting Group Chemistry: Utilized for the temporary protection of dihydroxy aromatic systems during multi-step synthetic sequences, enabling orthogonal deprotection strategies.
• Research & Development: A valuable tool for academic and industrial R&D laboratories exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	[2,5-Bis(Trimethylsilyloxy)Phenyl]Acetic Acid Methyl Ester
CAS No.	27798-63-6
Molecular Formula	C16H28O4Si2
Molecular Weight	340.57 g/mol
Synonyms	Methyl [2,5-bis(trimethylsilyloxy)phenyl]acetate; Methyl 2-[2,5-Bis(trimethylsiloxy)phenyl]acetate; Acetic acid, [2,5-bis[(trimethylsilyl)oxy]phenyl]-, methyl ester; 2,5-Bis-O-(trimethylsilyl)methyl phenylacetate; Methyl (2,5-Bis(trimethylsilyloxy)phenyl)acetate
EINECS	Contact for details

Quality Control

Our production of [2,5-Bis(Trimethylsilyloxy)Phenyl]Acetic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with every shipment, ensuring full traceability and compliance with your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed when not in use to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.