Description

8-[(2S,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-Chroman-3-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One is a high-purity, complex flavonoid dimer of significant interest in advanced research and development. This compound matters for its role as a key reference standard and a potential bioactive intermediate in the synthesis of novel pharmaceutical agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and manufacturers of high-value nutraceuticals focusing on polyphenol chemistry and natural product derivatives.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in drug discovery pipelines.
• Bioactive Compound Research: Serves as a critical intermediate or lead compound in studies investigating antioxidant, anti-inflammatory, or other therapeutic mechanisms.
• Nutraceutical Development: Employed in the formulation and standardization of high-end dietary supplements targeting specific health benefits.
• Chemical Synthesis: Acts as a sophisticated building block for the semi-synthesis of novel flavonoid derivatives and complex natural product analogs.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, phytochemistry, and pharmacology.
• Analytical Testing Services: Provided to contract research organizations (CROs) and testing labs as a high-purity calibrant for HPLC, LC-MS, and NMR analysis.

Basic Information

Product Name	8-[(2S,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-Chroman-3-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One
CAS No.	27542-37-6
Molecular Formula	C30H20O10
Molecular Weight	540.47 g/mol
Synonyms	Procyanidin B2; Procyanidol B2; Epicatechin-(4β→8)-epicatechin; Epicatechin dimer B2; (+)-Epicatechin-(4β→8)-(-)-epicatechin; [8]-[Epicatechin-(4→8)]-epicatechin; 27542-37-6; Procyanidin B-2
EINECS	Contact for details

Quality Control

Our 8-[(2S,3R)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-Chroman-3-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Keep container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.