Description

Methyl 6-Chloro-4-Oxo-4H-Chromene-2-Carboxylate is a high-purity chromene derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with chromene or benzopyran cores, which exhibit a wide range of biological activities.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Fine Chemical Synthesis: Serves as a precursor for dyes, pigments, and fluorescent markers due to the chromene structure's optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cyclization and functional group transformation reactions.
• Material Science Precursor: Potential starting material for synthesizing organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 6-Chloro-4-Oxo-4H-Chromene-2-Carboxylate
CAS No.	27455-31-8
Molecular Formula	C11H7ClO4
Molecular Weight	238.62 g/mol
Synonyms	Methyl 6-chloro-4-oxo-4H-1-benzopyran-2-carboxylate; 6-Chloro-4-oxo-4H-chromene-2-carboxylic acid methyl ester; 2-Carbomethoxy-6-chloro-4-chromone; 6-Chloro-4-oxochromene-2-carboxylic acid methyl ester; Methyl 6-chloro-4-oxochromene-2-carboxylate; 6-Chloro-2-(methoxycarbonyl)-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our Methyl 6-Chloro-4-Oxo-4H-Chromene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.