Description

(-)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-4H-1-Benzopyran-4-One is a high-purity chiral flavanone derivative of significant interest in advanced research and development. This compound serves as a critical building block and reference standard for pharmaceutical and nutraceutical applications due to its specific stereochemistry and biological activity profile. It is primarily utilized by research institutions, pharmaceutical R&D labs, and fine chemical manufacturers engaged in developing novel therapeutic agents and high-value bioactive ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates targeting inflammation, metabolic disorders, and neurological conditions.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies, receptor binding assays, and metabolic pathway analysis.
• Natural Product Synthesis: Serves as a core structure for the semi-synthesis or total synthesis of complex natural flavonoids and their analogs.
• Nutraceutical Development: Investigated for incorporation into advanced dietary supplements and functional foods due to its potential bioactive properties.
• Cosmeceutical Applications: Evaluated as an active ingredient in premium skincare formulations for its antioxidant and potential skin-beneficial effects.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	(-)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-4H-1-Benzopyran-4-One
CAS No.	27435-03-6
Molecular Formula	C₁₇H₁₆O₆
Molecular Weight	316.31 g/mol
Synonyms	(-)-5,7-Dihydroxy-3-(4-hydroxybenzyl)-6-methoxy-2,3-dihydro-4H-chromen-4-one; (2S)-5,7-Dihydroxy-3-[(4-hydroxyphenyl)methyl]-6-methoxy-2,3-dihydro-4H-chromen-4-one; (-)-Dihydrokaempferide 4'-methyl ether; (-)-3,4'-Dihydroxy-5,7-dimethoxyflavanone; Flavanone derivative 27435-03-6; (S)-Flavanone derivative; Ligustrin (related compound).
EINECS	Contact for details

Quality Control

Our (-)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-4H-1-Benzopyran-4-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as chiral purity, assay, and impurity profiles are provided and available upon request. We support development projects with custom purity grades and analytical method support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% (S-enantiomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.