Description

1-tert-Butylcyclohexanecarboxylic Acid is a versatile, sterically hindered alicyclic carboxylic acid that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a bulky tert-butyl group adjacent to the carboxyl function, makes it invaluable for introducing conformational rigidity and lipophilicity into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a rigid, lipophilic cyclohexane scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the tert-butylcyclohexyl moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts in asymmetric synthesis, leveraging its steric bulk to influence stereoselectivity.
• Polymer Modification: Incorporated as a monomer or modifier to create polymers with enhanced thermal stability, chemical resistance, and specific mechanical properties.
• Fragrance and Flavor Chemistry: Utilized in the synthesis of musk analogs and other complex aroma chemicals due to its stable, bulky structure.
• Material Science Research: Acts as a model compound or building block for developing liquid crystals, organic semiconductors, and other advanced functional materials.

Basic Information

Product Name	1-tert-Butylcyclohexanecarboxylic Acid
CAS No.	27334-43-6
Molecular Formula	C11H20O2
Molecular Weight	184.28 g/mol
Synonyms	1-(1,1-Dimethylethyl)cyclohexanecarboxylic Acid; 1-tert-Butyl-1-cyclohexanecarboxylic Acid; trans-1-tert-Butylcyclohexane-1-carboxylic Acid; Cyclohexanecarboxylic acid, 1-(1,1-dimethylethyl)-; 1-t-Butylcyclohexanecarboxylic Acid; TBCHA; NSC 163022
EINECS	Contact for details

Quality Control

Our 1-tert-Butylcyclohexanecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-compliant pharmaceutical synthesis and other high-value industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 105 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.