Description

(-)-2,3-Dihydro-7-Hydroxy-3-[(4-Hydroxyphenyl)Methyl]-5-Methoxy-4H-1-Benzopyran-4-One is a high-purity chiral flavanone derivative with significant biological activity. This compound is valued for its role as a key synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for the synthesis of bioactive molecules and analytical applications.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation and metabolic disorders.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Biochemical Research: Employed in in vitro studies to investigate biological pathways, enzyme inhibition, and receptor binding activities due to its specific stereochemistry.
• Natural Product Synthesis: Acts as a precursor in the semi-synthesis or total synthesis of complex natural products and flavonoids.
• Cosmeceutical R&D: Explored for potential applications in advanced skincare formulations targeting antioxidant and anti-aging mechanisms.

Basic Information

Product Name	(-)-2,3-Dihydro-7-Hydroxy-3-[(4-Hydroxyphenyl)Methyl]-5-Methoxy-4H-1-Benzopyran-4-One
CAS No.	27245-81-4
Molecular Formula	C₁₇H₁₆O₅
Molecular Weight	300.31 g/mol
Synonyms	(-)-7-Hydroxy-3-(4-hydroxybenzyl)-5-methoxy-2,3-dihydrochromen-4-one; (3S)-7-Hydroxy-3-[(4-hydroxyphenyl)methyl]-5-methoxy-2,3-dihydro-4H-chromen-4-one; (S)-7-Hydroxy-3-(4-hydroxybenzyl)-5-methoxy-2,3-dihydro-4H-chromen-4-one; 3S-7-Hydroxy-3-(4-hydroxybenzyl)-5-methoxy-2,3-dihydro-4H-chromen-4-one; (-)-3S-Dihydro-7-hydroxy-3-(4-hydroxybenzyl)-5-methoxy-4H-1-benzopyran-4-one; Flavanone derivative 27245-81-4; (S)-Flavanone derivative. Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (-)-2,3-Dihydro-7-Hydroxy-3-[(4-Hydroxyphenyl)Methyl]-5-Methoxy-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.