Description

(7E,9ξ)-9-Hydroxy-5,7-Megastigmadien-4-One CAS NO 27185-78-0 is a high-purity, naturally derived ketone belonging to the megastigmane class of compounds. This specialty intermediate is valued for its unique structural framework, which serves as a versatile building block in the synthesis of complex flavor, fragrance, and bioactive molecules. It is primarily sought after by R&D chemists and production specialists in the flavor & fragrance, pharmaceutical, and fine chemical industries for creating novel organoleptic profiles and advanced synthetic targets.

Application

• Flavor & Fragrance (F&F) Industry: A key chiral intermediate for the synthesis of sophisticated tobacco, tea, and fruity flavor notes, such as damascones and ionones.
• Pharmaceutical Research: Serves as a crucial scaffold or precursor in the synthesis of novel bioactive compounds and natural product analogs for drug discovery programs.
• Fine Chemical Synthesis: Used as a building block for producing other high-value specialty chemicals, including carotenoids and other terpenoid derivatives.
• Natural Product Chemistry: Employed as a reference standard or starting material in academic and industrial research focused on megastigmane and norisoprenoid chemistry.
• Cosmetic Ingredients: Potential intermediate for creating specialty aroma chemicals used in premium perfumery and cosmetic formulations.

Basic Information

Product Name	(7E,9ξ)-9-Hydroxy-5,7-Megastigmadien-4-One
CAS No.	27185-78-0
Molecular Formula	C₁₃H₂₀O₂
Molecular Weight	208.30 g/mol
Synonyms	9-Hydroxy-5,7-megastigmadien-4-one; (7E,9E)-9-Hydroxy-5,7-megastigmadien-4-one; 4-(3-Hydroxybut-1-en-1-yl)-3,5,5-trimethylcyclohex-2-en-1-one; Megastigma-5,7-dien-4-one, 9-hydroxy-; Theaspirone precursor; Norisoprenoid intermediate; Megastigmane ketone
EINECS	Contact for details

Quality Control

Every batch of (7E,9ξ)-9-Hydroxy-5,7-Megastigmadien-4-One is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.