Description

(3R)-3,6-Dihydro-6α-Methoxy-2H-Pyran-3α-Ol Acetate is a chiral, functionalized dihydropyran derivative that serves as a valuable synthetic intermediate. Its precise stereochemistry and protected functional groups make it a critical building block for the synthesis of complex natural products and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct stereochemically defined molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those containing tetrahydropyran or sugar-like motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Natural Product Synthesis: Serves as a crucial precursor for constructing the core structures of various natural products, including macrolides and polyether antibiotics.
• Asymmetric Catalysis Research: Employed as a standard or test substrate in the development and optimization of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	(3R)-3,6-Dihydro-6α-Methoxy-2H-Pyran-3α-Ol Acetate
CAS No.	26532-19-4
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(3R)-3,6-Dihydro-6-methoxy-2H-pyran-3-yl acetate; (3R)-6-Methoxy-3,6-dihydro-2H-pyran-3-yl acetate; 6-Methoxy-3,6-dihydro-2H-pyran-3-ol, acetate, (3R)-; 3-Acetoxy-6-methoxy-3,6-dihydro-2H-pyran; (R)-6-Methoxy-3,6-dihydro-2H-pyran-3-yl acetate
EINECS	Contact for details

Quality Control

Our (3R)-3,6-Dihydro-6α-Methoxy-2H-Pyran-3α-Ol Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.