Description

Valeric Acid Trimethylsilyl Ester is a versatile organosilicon reagent used primarily as a silylating agent and a protected synthetic intermediate. This compound is valued for its ability to introduce the trimethylsilyl (TMS) group, enhancing the volatility and stability of target molecules for analytical and synthetic purposes. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require reliable, high-purity intermediates for complex synthesis.

Application

• Derivatization Agent in GC/MS Analysis: Used to silylate carboxylic acids, alcohols, and other polar functional groups to improve their thermal stability and detectability in gas chromatography-mass spectrometry.
• Pharmaceutical Intermediate: Serves as a key protected intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly where temporary protection of a carboxylic acid group is required.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides as a building block or protecting group reagent.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of specialized silicone-based polymers and advanced materials.
• Organic Synthesis Reagent: Facilitates various reactions, including esterifications and condensations, where the TMS ester functionality is leveraged for its specific reactivity.
• Flavor & Fragrance Industry: Used in the synthesis of complex ester compounds that contribute to specific flavor and aroma profiles.

Basic Information

Item	Details
Product Name	Valeric Acid Trimethylsilyl Ester
CAS No.	26429-16-3
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	Pentanoic Acid Trimethylsilyl Ester; Trimethylsilyl Valerate; TMS-Valerate; n-Valeric Acid Trimethylsilyl Ester; Valeric Acid TMS Ester; Trimethylsilyl Pentanoate; Butanecarboxylic Acid Trimethylsilyl Ester; 1-Butanecarboxylic Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our Valeric Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.