Description

[1R-(1Alpha,2Beta,5Alpha)]-p-Menthyl Phenylacetate CAS NO 26171-78-8 is a high-purity, chiral aromatic ester derived from menthol and phenylacetic acid. This compound is valued for its specific stereochemistry and clean aromatic profile, making it a critical intermediate for advanced synthesis. It is primarily sought by manufacturers in the fragrance, flavor, and pharmaceutical industries for creating sophisticated, high-value end products.

Application

• Fragrance Industry: A key chiral building block for high-end synthetic musks, amber notes, and other complex aromatic compounds requiring specific stereochemical purity.
• Flavor Industry: Used as a chiral intermediate in the synthesis of specific flavoring agents where the isomeric purity influences the sensory profile.
• Pharmaceutical Intermediates: Serves as a valuable chiral synthon in the research and development of active pharmaceutical ingredients (APIs) with defined stereocenters.
• Fine Chemical Synthesis: Employed in asymmetric synthesis and other advanced organic reactions as a stereochemically defined starting material or auxiliary.
• Research & Development: Utilized in academic and industrial R&D for studying stereoselective reactions and developing new synthetic methodologies.

Basic Information

Product Name	[1R-(1Alpha,2Beta,5Alpha)]-p-Menthyl Phenylacetate
CAS No.	26171-78-8
Molecular Formula	C19H28O2
Molecular Weight	288.43 g/mol
Synonyms	(-)-Menthyl Phenylacetate; L-Menthyl Phenylacetate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Phenylacetate; p-Menth-3-yl Phenylacetate; Phenylacetic Acid (-)-Menthyl Ester; FEMA 3748; (1R,2S,5R)-Menthyl Phenylacetate; (1R)-(-)-Menthyl Phenylacetate
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,2Beta,5Alpha)]-p-Menthyl Phenylacetate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for fragrance, flavor, and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Specific Rotation [α]20/D	-70° to -80° (c=1 in CHCl3)
Assay (GC)	≥ 98.0%
Chiral Purity (GC/HPLC)	≥ 99.0% (diastereomeric excess)
Refractive Index n20/D	1.495 - 1.505
Relative Density (20°C)	0.980 - 1.010

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.