Description

Polyglycidol is a versatile, multi-functional polyether polyol characterized by its pendant hydroxyl groups on a polyglycidyl backbone. This unique structure makes it a valuable reactive intermediate and building block for creating advanced polymers with tailored properties. It is particularly sought after by R&D and production teams in the pharmaceutical, specialty chemical, and advanced materials sectors. Polyglycidol CAS NO 25722-70-7 is engineered for applications requiring precise functionality and consistent performance.

Application

• Pharmaceutical Excipient & Drug Conjugation: Used as a hydrophilic linker or carrier in prodrug design and for modifying the pharmacokinetic profiles of active pharmaceutical ingredients (APIs).
• Hydrogel Synthesis: Serves as a key monomer or crosslinker for creating biocompatible and stimuli-responsive hydrogels used in medical devices and tissue engineering.
• Surface Modification & Coatings: Imparts hydrophilicity and functional groups to surfaces for anti-fouling coatings, biosensors, and chromatographic media.
• Polymer Functionalization: Acts as a macroinitiator or macromonomer for synthesizing complex architectures like star polymers, dendrimers, and graft copolymers.
• Adhesive & Sealant Formulations: Contributes to the flexibility, adhesion, and moisture-curing properties of advanced polyurethane and epoxy-based systems.
• Personal Care & Cosmetics: Utilized as a film-forming agent, emulsifier, or viscosity modifier in advanced cosmetic formulations.

Basic Information

Product Name	Polyglycidol
CAS No.	25722-70-7
Molecular Formula	(C3H6O2)n
Molecular Weight	Variable (dependent on degree of polymerization)
Synonyms	Poly(2,3-epoxy-1-propanol); Poly(oxymethyl)ethylene glycol; Poly(glycidyl alcohol); Poly(2-hydroxyethyl oxirane); Poly(oxy-2,3-epoxypropyl); Glycidol homopolymer; Hydroxyl-functional poly(ethylene oxide); PGL
EINECS	Contact for details

Quality Control

Our Polyglycidol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistent molecular weight distribution, functionality, and purity. We provide detailed Certificates of Analysis (COA) that include key parameters such as hydroxyl value, polydispersity index (PDI), and residual monomer content. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). To prevent moisture uptake and potential polymerization, containers must be kept tightly sealed after opening and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (Hydroxyl Value)	As per COA (Typical range: 7-11 mmol/g)
Number Average Molecular Weight (Mn)	As per COA (e.g., 500, 1000, 2000 g/mol)
Polydispersity Index (PDI)	< 1.5 (GPC)
Residual Glycidol	< 100 ppm (GC)
Water Content	< 0.5% (KF Titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.