Description

1,1'-[(E)-Vinylene]Bis[3-[(Tetrahydro-2H-Pyran-2-Yl)Methyl]Urea] is a specialized chemical intermediate featuring a unique bis-urea structure with tetrahydropyranyl protecting groups. This compound matters for its role as a versatile building block in advanced organic synthesis, particularly in the development of pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates requiring urea-linked scaffolds.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating novel polyurea or polyurethane materials with specific thermal or mechanical properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides or fungicides that utilize its bis-urea functionality.
• Chemical Biology & Proteomics: Potential use in designing enzyme inhibitors or molecular probes that target urea-recognizing biological sites.
• Material Science Research: Employed in developing advanced organic frameworks, coatings, or adhesives where its structural rigidity is beneficial.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on laboratory to pilot scale.

Basic Information

Product Name	1,1'-[(E)-Vinylene]Bis[3-[(Tetrahydro-2H-Pyran-2-Yl)Methyl]Urea]
CAS No.	25689-71-8
Molecular Formula	C₁₇H₂₈N₄O₅
Molecular Weight	368.43 g/mol
Synonyms	N,N'-(1E)-1,2-Ethenediylbis[N-[(tetrahydro-2H-pyran-2-yl)methyl]urea]; 1,1'-(1E)-Ethene-1,2-diylbis(3-[(tetrahydro-2H-pyran-2-yl)methyl]urea); (E)-1,1'-(Ethene-1,2-diyl)bis(3-((tetrahydro-2H-pyran-2-yl)methyl)urea); THP-Protected Bis-Urea Vinylene Derivative; CAS 25689-71-8
EINECS	Contact for details

Quality Control

Our 1,1'-[(E)-Vinylene]Bis[3-[(Tetrahydro-2H-Pyran-2-Yl)Methyl]Urea] is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.