Description

2,2-Dimethyl-n-(4-Trifluoromethyl-Phenyl)-Propionamid is a specialized organic compound featuring a trifluoromethylphenyl group, a key structural motif valued in advanced chemical synthesis. This compound serves as a crucial high-purity intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated aromatic system imparts desirable biological activity and metabolic stability. It is primarily required by R&D laboratories and fine chemical manufacturers engaged in creating novel molecules for the pharmaceutical and crop protection industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in organic chemistry research to create novel ligands for metal-catalyzed reactions or organocatalysts.
• Fluorine Chemistry Studies: Acts as a standard or reagent in academic and industrial research focused on incorporating fluorine into organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2,2-Dimethyl-n-(4-Trifluoromethyl-Phenyl)-Propionamid
CAS No.	25617-34-9
Molecular Formula	C12H14F3NO
Molecular Weight	245.24 g/mol
Synonyms	N-(4-(Trifluoromethyl)phenyl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-[4-(trifluoromethyl)phenyl]propanamide; α,α-Dimethyl-4-(trifluoromethyl)benzenepropanamide; p-Trifluoromethyl-α,α-dimethylphenylacetamide; Propanamide, 2,2-dimethyl-N-[4-(trifluoromethyl)phenyl]-; Amide, 2,2-dimethyl-N-(4-trifluoromethylphenyl)propion-
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-n-(4-Trifluoromethyl-Phenyl)-Propionamid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.