Description

(2S)-3α-Hydroxymethyl-3,4-Dihydro-2β-Methyl-4α-[(9-Methyl-9H-Pyrido[3,4-B]Indol-1-Yl)Methyl]-2H-Pyran-5-Carboxylic Acid Methyl Ester is a complex, high-purity synthetic intermediate characterized by its fused pyran and pyridoindole ring systems. This compound matters for its role as a critical building block in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs) with complex heterocyclic frameworks.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting neurological or oncological pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes for novel compounds, requiring high chemical purity and consistent batch-to-batch quality.
• Reference Standard: Acts as an analytical standard for quality control and method development in laboratories characterizing related compounds.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized, high-value chemicals for advanced material science or agrochemical research.

Basic Information

Product Name	(2S)-3α-Hydroxymethyl-3,4-Dihydro-2β-Methyl-4α-[(9-Methyl-9H-Pyrido[3,4-B]Indol-1-Yl)Methyl]-2H-Pyran-5-Carboxylic Acid Methyl Ester
CAS No.	25394-75-6
Molecular Formula	C24H26N2O5
Molecular Weight	422.48 g/mol
Synonyms	Methyl (2S,3S,4R)-3-(hydroxymethyl)-2-methyl-4-[(9-methyl-9H-β-carbolin-1-yl)methyl]-3,4-dihydro-2H-pyran-5-carboxylate; 1-[[(2S,3S,4R)-5-(Methoxycarbonyl)-2-methyl-3,4-dihydro-2H-pyran-3,4-diyl]bis(methylene)]-9-methyl-9H-pyrido[3,4-b]indole; (2S,3S,4R)-3-(Hydroxymethyl)-2-methyl-4-[(9-methyl-9H-pyrido[3,4-b]indol-1-yl)methyl]-3,4-dihydro-2H-pyran-5-carboxylic acid methyl ester; 25394-75-6; (2S)-3α-Hydroxymethyl-3,4-dihydro-2β-methyl-4α-[(9-methyl-9H-pyrido[3,4-b]indol-1-yl)methyl]-2H-pyran-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (2S)-3α-Hydroxymethyl-3,4-Dihydro-2β-Methyl-4α-[(9-Methyl-9H-Pyrido[3,4-B]Indol-1-Yl)Methyl]-2H-Pyran-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with exacting research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.