Description

4-Methyl-1-(Trifluoroacetyl)-3-Thiosemicarbazide is a specialized organofluorine building block and a key intermediate in heterocyclic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel thiadiazole, triazole, and other nitrogen-sulfur heterocycles with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the trifluoroacetyl and thiosemicarbazide functionalities.
• Coordination Chemistry: Serves as a versatile ligand for metal complexation, useful in catalysis and materials science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and biological pathways.
• Polymer Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance.
• Dye and Pigment Synthesis: An intermediate for creating complex chromophores and functional dyes.

Basic Information

Product Name	4-Methyl-1-(Trifluoroacetyl)-3-Thiosemicarbazide
CAS No.	25366-21-6
Molecular Formula	C5H6F3N3OS
Molecular Weight	201.18 g/mol
Synonyms	1-(Trifluoroacetyl)-4-methyl-3-thiosemicarbazide; 4-Methyl-1-(trifluoroacetyl)thiosemicarbazide; 1-Methyl-5-(trifluoroacetyl)imino-2-thiobiuret; N-(Trifluoroacetyl)-N'-methylhydrazinecarbothioamide; 3-Thiosemicarbazide, 4-methyl-1-(trifluoroacetyl)-; Trifluoroacetic acid (4-methyl-3-thiosemicarbazide)
EINECS	Contact for details

Quality Control

Our 4-Methyl-1-(Trifluoroacetyl)-3-Thiosemicarbazide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.