Description

α-[4-(3,4-Dihydroxyphenyl)-3-Hydroxy-5-Oxofuran-2(5H)-Ylidene]-4-Hydroxybenzeneacetic Acid is a specialized organic compound with a complex polyphenolic and furanone-based structure, making it a valuable intermediate for advanced chemical synthesis. This compound matters for its role as a key building block in the development of high-value fine chemicals, pharmaceuticals, and functional materials. Industries requiring sophisticated organic synthesis, such as pharmaceutical R&D, agrochemical development, and specialty chemical manufacturing, are the primary users of this high-purity intermediate.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting oxidative stress-related pathways.
• Biochemical Research: Used as a reference standard or probe in studying antioxidant mechanisms, enzyme inhibition, and free radical scavenging activities.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex molecules with specific electronic or photochemical properties for material science applications.
• Agrochemical Development: Employed in research for developing new plant growth regulators or protective agents due to its polyphenolic structure.
• Cosmetic Ingredient Research: Investigated for potential use in premium skincare formulations aimed at providing antioxidant benefits.
• Polymer Chemistry: Can be utilized to introduce functional phenolic groups into polymer chains to modify material properties like UV absorption or adhesion.

Basic Information

Product Name	α-[4-(3,4-Dihydroxyphenyl)-3-Hydroxy-5-Oxofuran-2(5H)-Ylidene]-4-Hydroxybenzeneacetic Acid
CAS No.	25287-88-1
Molecular Formula	C18H12O8
Molecular Weight	356.28 g/mol
Synonyms	4-Hydroxybenzeneacetic acid, α-[4-(3,4-dihydroxyphenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene]-; 2-(3,5-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-pyran-3-carboxylic acid (tautomeric form); 3-Hydroxy-2-[(3,4-dihydroxyphenyl)methylene]-4-oxo-4H-furan-5-carboxylic acid; Rosmarinic acid lactone derivative; Polyphenolic furanone acid; Caffeic acid cyclic lactone derivative; 25287-88-1; α-Hydroxybenzeneacetic acid derivative
EINECS	Contact for details

Quality Control

Our α-[4-(3,4-Dihydroxyphenyl)-3-Hydroxy-5-Oxofuran-2(5H)-Ylidene]-4-Hydroxybenzeneacetic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing all critical parameters, including assay by HPLC, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for demanding R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame. The container must be kept tightly sealed to minimize exposure to atmospheric moisture and oxygen.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.